Verrutop, the revolution in topical treatment for difficult warts

Types of warts

Verrutop is a topical solution for professional use providing painless treatment of difficult warts that is highly effective in just a few applications.

With Nitrizinc Complex:

A unique, elevated combination
  • Nitric acid
  • Organic acids
  • Zn and Cu salts

Types of warts

*As sensitivity varies, some patients may experience a slight, short-lived tingling after application of the product. This disappears after a few seconds.

Use under medical supervision

Class IIA Healthcare Product

4 ampoules 100 μl Nitrizinc Complex®

4 ampoules 100 μll Nitrizinc Complex®

Applicator capillaries verrutop

Applicator capillaries

Instruction booklet verrutop

Instruction booklet

How do you apply Verrutop?

Verrutop is easy and quick to apply. It doesn’t require any special equipment and doesn’t affect the patient’s daily life.

Apply Verrutop: 1. Break the ampoule

Break the ampoule

Apply Verrutop: 2. Insert the capillary

Insert the capillary

to extract Verrutop®

Apply Verrutop: 3. Fill the applicator

Fill the applicator

with the product

Apply Verrutop: 4. Apply the product

Apply the product

with the capillary directly on the wart

Apply the necesary quantity of product to cover the wart according to its size but always avoid excess. If re-application is necessary wait 15 to 30 seconds between applications. The patient must be assessed by a health professional after a minimum period of 1 to 2 weeks, depending on the location to evaluate elimination of the wart or to re-apply the product if necessary. Treatment could be repeated for up to a maximum of six sessions, separated by a minimum period of 7 days. Check the product information leaflet for further information and warnings.

See how to eliminate verrucas with Verrutop® with Dr Ogalla. See video

Quick and painless* application

One applied to the warts, it produces a painless mummification of the damaged tissue that causes the wart to detach automatically as healthy skin forms.

Topical painless and effective treatment of difficult warts

Topical painless and effective treatment of difficult warts

The tissue loses vitality

as a result of the chemical reaction between organic acids and metal ions in the nitric acid

Topical painless and effective treatment of difficult warts

Wart colour changes

to white/yellowish

Topical painless and effective treatment of difficult warts

Mummification of the tissue

that darkens gradually

Topical painless and effective treatment of difficult warts

Cell renewal

progressively under the protective layer

Topical painless and effective treatment of difficult warts

Wart detaches

automatically a few days later

Proven efficacy,
even in the most difficult cases


of patients cured after a maximum of 6 treatment sesions1. Average: 3 sessions .

Número de aplicaciones de Verrutop


of patients cured after a maximum of 4 treatment sessions2. 49% of them cured after only one session

Efficacy in palmoplantar warts resistant to cryotherapy3


responded totally or partially to treatment with Verrutop®

% cure plantar wartss

% cured plantar warts


disappeared after 1-3 applications of Verrutop®

Applications of Verrutop

Number of applications

With Verrutop, the complete viral DNA elimination occurs in 40% of cases,
while no effect was achieved by liquid nitrogen4

Verrutop reduces DNA virus by 40% while cryotherapy doesn't lead to any regression

*. Verrutop in general is a painless treatment , altough some people may experience some temporary discomfort thatranges from a burning to slight tenderness or pain. 1. Galloni C, Balice Y, Fachetti M, Marchetti S, Motta L, Pisacane D. Efficacy and tolerability assessment of a new medical device containing a nitric-zinc complex to treat palmar, plantar and periungual warts: experience with 210 patients. Poster session presented at 27th EADV Congress; 2018 Sep 12-16; France, Paris. 2. Ciccarese G. Efficacy Assessment of a Topically Applied Nitric–Zinc Complex Solution for the Treatment of External Anogenital Warts in 100 Patients. Dermatol Ther (Heidelb). 2019 Jun;9(2):327-335 3. . Guillet G, Jéroche F. Evaluation de l’efficacité et de la tolérance d’un traitement de verrues palmo-plantaires après échec thérapeutique avec cryothérapie, et de verrues péri-unguéales. Poitiers, France, Dermatologie pratique N°363-octobre 2012, p.9-10. 4. Viennet C et al. Assessment of the efficacy of a new formulation for plantar wart mummification: new experimental design and human papillomavirus identification .CED a 2012 British Association of Dermatologists Clinical and Experimental Dermatology, 38, 85–88