Bexident Post treatment adjuvant A leader in triple-action, post-surgical treatment1

Bexident Post

Regenerating and healing action. Broad-spectrum antiseptic. Reduces inflammation.

Excellent clinical efficacy in more than 1000 patients2

Only in gel and mouthwash format

International experience

Chitoheal Tech® Healing

Chitosan + Chlorhexidine 0,2%

Cranpearls Tech

Tecnología ChitoHealTech®

The Bexident® Post range of products with Chitoheal Tech® technology features an innovative combination of chitosan and chlorhexidine 0.2%, for regenerative, healing and antiseptic action. Allantoin and Dexpanthenol reduce inflammation and bleeding of the gums. Long-lasting action (bioadhesive excipient). Reduces the need for analgesics when applied after surgery. Helps to reduce inflammation and regenerate the gums and oral mucosa in periodontal and peri-implant treatments.

Active ingredients with proven efficacy and safety

Chitosan

Biologically active polymer

* Healing action7

* Reepithelialising action8,9

* Haemostatic action 10

* Mucoadhesive action due to its positive charge11

* Antimicrobial action12


Proven safety

No allergic response in patients with a shellfish allergy13, 14

Chlorhexidine 0,2%

Provides an antiseptic action

Dexpanthenol and Allantoin

Help to reduce inflammation and repair gums and the epithelial mucosa

Bioadhesive excipient

Long-lasting action

Chitosan

Chitosan (or quitosan) is a natural polysaccharide. It is obtained through a process of partial deacetylation of chitin, a polymer that forms part of the exoskeleton of crustaceans and insects and is also present in some fungi14. It is a polymer of N-acetylglucosamines and Glucosamines, biocompatible and biodegradable through liposomes. Its physiochemical characteristics make it useful for preparing pharmaceutical products and its beneficial biological properties justify its use in medicine 7, 14.

Clinically-proven efficacy

Gargallo J., et al. In vitro demonstration of the healing and anti-inflammatory effect of a gingival gel. Poster presented at the 7th National Congress of the Spanish Society of Oral Surgery. Almeria, 2009.

López López, J. E fficacy of chlorhexidine, ganciclovir, allantoin and chitosan gel in comparison with oral bicarbonate rinse in controlling post-interventional and inflammation, pain and cicatrisation in subjects undergoing dental surgery. Current Medical Research & Opinion 2015, 1-5.

Bexident Post Mouthwash

Bexident Post Topical gel

What you didn’t know about surgery

Risks after operation

After a surgical process, certain risks can appear, such as infection or problems with tissue healing.

Treatment

It is important to use products that have a triple action: preventing infection after the intervention, helping tissues heal and reducing inflammation

1. Unidades vendidas de productos con efecto Regenerador, Antiséptico y Antiinflamatorio en tratamiento postquirúrgico. Datos de IQVIA España, YTD Agosto 2018. 2. Estudio EPIMO (Evaluación de la efectividad de Bexident Post Gel Tópico en la cicatrización de las heridas de la mucosa oral), 2011. 3. Unidades vendidas de Bexident Post en España, Portugal y México. Datos de: IQVIA España, hmR Portugal, Gknoblock México. 4. Unidades vendidas de Bexident Post en España, Portugal y México desde Sept. 2009 a Abril 2018. Datos de: IQVIA España, hmR Portugal, Gknoblock México. Estimación : 1 unidad vendida = 1 paciente tratado. 5. Gargallo J., et al. Demostración in vitro del efecto cicatrizante y antiinflamatorio de un gel gingival. Póster presentado en el VII Congreso Nacional de la Sociedad Española de Cirugía Bucal. Almería, 2009. 6. López López, J. Ecacy of chlorhexidine, dexpanthenol, allantoin and chitosan gel in comparison with bicarbonate oral rinse in controlling post-interventional inflammation, pain and cicatrization in subjects undergoing dental surgery. Current Medical Research & Opinion 2015, 1–5. 7. Ueno H, Mori T, Fujinaga T. Topical formulations and wound healing applications of chitosan. Adv Drug Deliv Rev. 2001;52(2):105-15. 8. Jin Y, Ling PX, He YL, Zhang TM. Eects of chitosan and heparin on early extension of burns. Burns. 2007;33(8):1027-31. 9. Alsarra IA. Chitosan topical gel formulation in the management of burn wounds. Int J Biol Macromol. 2009;45(1):16-21. 10. Recinos G, Inaba K, Dubose J, Demetriades D, Rhee P. Local and systemic hemostatics in trauma: a review. Ulus Travma Acil Cerrahi Derg. 2008;14(3):175-81. 11. Patel, D., Smith, A. W., Grist, N., Barnett, P., Smart, J. D. (1999) An in vitro mucosal model predictive of bioadhesive agents in the oral cavity. J. Control. Rel. 1999; 61: 175-183. 12. Singla AK, Chawla M. Chitosan: some pharmaceutical and biological aspects--an update. J Pharm Pharmacol. 2001;53(8):1047-67. 13. Waibel KH1 et AlSafety of chitosan bandages in shellfish allergic patients. Mil Med. 2011 Oct;176(10):1153-6. 14. Smith et al. Chitosan A promising safe and immune-enhancing adjuvant for intranasal vaccinesHuman Vaccines & Immunotherapeutics 10:3, 797–807; March 2014.


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