Bexident® Post Chitoheal Tech Healing Chitosan + Chlorhexidine 0,2%

Bexident Post

Expert post-intervention treatment

Unique ingredients combination

Available in gel and mouthwash format to adapt to all needs

International experience

Chitoheal Tech® Healing

Chitosan + Chlorhexidine 0,2%

Cranpearls Tech

TTecnologia Chitoheal Tech® Technology

The Bexident® Post range of products features Chitoheal Tech technology, an innovative combination of Chitosan and Chlorhexidine 0.2%, that promotes epithelial regeneration of the gums and oral mucosa after periodontal processes. It also helps reduce spread of bacteria and biofilm formation. Its bio-adhesive formula offers long-lasting action. Specially indicated for use after periodontal, peri-implant and maxillofacial surgery.

Active ingredients with proven efficacy and safety

Chitosan

Biologically active polymer:

* Healing action4

* Regenerating action5,6

* Haemostatic action 7

* Mucoadhesive action due to its positive charge8

* Antimicrobial action9


Chlorhexidine 0,2%

Helps prevent formation of biofilm and bacterial plaque.

Dexpanthenol and Allantoin

Calming and soothing action. Contributes to healthier gums.

Bioadhesive excipient

Long-lasting action

Chitosan

Chitosan (or quitosan) is a natural polysaccharide. It is obtained through a process of partial deacetylation of chitin, a polymer that forms part of the exoskeleton of crustaceans and insects and is also present in some fungi14. It is a poymer of N-acetylglucosamines and glucosamines, biocompatible and biodegradable through liposomes. Its physiochemical characteristics make it useful for preparing pharmaceutical products and thanks to its beneficial biological properties, it is used in wound healing products7.14.

Clinically-proven efficacy

2. Gargallo J., et al. In vitro demonstration of the healing and anti-inflammatory effect of a gingival gel. Poster presented at the 7th National Congress of the Spanish Society of Oral Surgery. Almeria, 2009.

3. López López, J. E fficacy of chlorhexidine, ganciclovir, allantoin and chitosan gel in comparison with oral bicarbonate rinse in controlling post-interventional and inflammation, pain and cicatrisation in subjects undergoing dental surgery. Current Medical Research & Opinion 2015, 1-5.

Bexident Post Mouthwash

Bexident Post Topical gel

What you didn’t know about surgery

Risks after operation

After a surgical process, certain risks can appear, such as infection or problems with tissue healing.

Treatment

It is important to use products that have a triple action: preventing infection after the intervention, helping tissues heal and reducing inflammation

1. Bexident Post units sold in post-surgery treatment. IQVIA Spain, YTD August 2018. 2. Gargallo J., et al. Demostración in vitro del efecto cicatrizante y antiinflamatorio de un gel gingival. Póster presentado en el VII Congreso Nacional de la Sociedad Española de Cirugía Bucal. Almería, 2009. 3. López López, J. Efficacy of clorhexidine, dexpanthenol, allantoin and chitosan gel in comparison with bicarbonate oral rinse in controlling post-interventional inflammation, pain and cicatrization in subjects undergoing dental surgery.Current Medical Research & Opinion 2015, 1-5. 4. Unidades vendidas de Bexident Post en España, Portugal y México desde Sept. 2009 a Abril 2018. Datos de: IQVIA España, hmR Portugal, Gknoblock México. Estimación : 1 unidad vendida = 1 paciente tratado. 5. Gargallo J., et al. Demostración in vitro del efecto cicatrizante y antiinflamatorio de un gel gingival. Póster presentado en el VII Congreso Nacional de la Sociedad Española de Cirugía Bucal. Almería, 2009. 6. López López, J. Ecacy of chlorhexidine, dexpanthenol, allantoin and chitosan gel in comparison with bicarbonate oral rinse in controlling post-interventional inflammation, pain and cicatrization in subjects undergoing dental surgery. Current Medical Research & Opinion 2015, 1–5. 7. Recinos G, Inaba K, Dubose J, Demetriades D, Rhee P. Local and systemic hemostatics in trauma: a review. Ulus Travma Acil Cerrahi Derg. 2008; 14(3):175-81. 8. Patel, D., Smith, A. W., Grist, N., Barnett, P., Smart, J. D. (1999) An in vitro mucosal model predictive of bioadhesive agents in the oral cavity. J. Control. Rel. 1999; 61: 175-183. 9. Singla AK, Chawla M. Chitosan: some pharmaceutical and biological aspects--an update. J Pharm Pharmacol. 2001;53(8):1047-67. 8. Jin Y, Ling PX, He YL, Zhang TM. Efects of chitosan and heparin on early extension of burns. Burns. 2007;33(8):1027-31. 9. Alsarra IA. Chitosan topical gel formulation in the management of burn wounds. Int J Biol Macromol. 2009;45(1):16-21. 10. Recinos G, Inaba K, Dubose J, Demetriades D, Rhee P. Local and systemic hemostatics in trauma: a review. Ulus Travma Acil Cerrahi Derg. 2008;14(3):175-81. 11. Patel, D., Smith, A. W., Grist, N., Barnett, P., Smart, J. D. (1999) An in vitro mucosal model predictive of bioadhesive agents in the oral cavity. J. Control. Rel. 1999; 61: 175-183. 12. Singla AK, Chawla M. Chitosan: some pharmaceutical and biological aspects--an update. J Pharm Pharmacol. 2001;53(8):1047-67. 13. Waibel KH1 et AlSafety of chitosan bandages in shellfish allergic patients. Mil Med. 2011 Oct;176(10):1153-6. 14. Smith et al. Chitosan A promising safe and immune-enhancing adjuvant for intranasal vaccinesHuman Vaccines & Immunotherapeutics 10:3, 797–807; March 2014.


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