If you’re the kind of person who loves trying out new things, and follows the latest skincare trends, ampoules may have popped up on your radar. If they haven’t, then you’re going to want to know all about them!
Ampoules have been a staple in European skincare routines for decades, recommended in dermatologists’ offices and pharmacies. They’re known for their concentrated formulas, elegant presentation, and, more importantly, their efficacy. In the USA, however, they’re still somewhat of a novelty. But not for long. Ampoules are finding their place on vanities, lining bathroom cabinets, and elevating skincare routines across the country.
Let’s take a closer look and discover how to use ampoules properly in your skincare routine, from which step to use them at, to opening and storing them correctly.
Table of Contents
Where do I use an ampoule in my skincare routine?
When first using an ampoule in your skincare routine, an important thing to remember is that the word ‘ampoule’ describes a unique package that is sealed and contains a serum – so the contents are ‘serums’ while the package is the ‘ampoule’. The serums used in ampoules generally use minimalist formulas, focusing on specific ingredients and ingredient combinations to provide your skin with targeted care. Skin ampoules are sometimes referred to as serums-in-ampoules, meaning it’s easier to define exactly what the package contains.

When thinking about products and how to order them in your skincare routine, it’s a good idea to focus on the texture, and remember this basic rule: light to heavy. Facial serums are typically lightweight, absorbing quickly into the skin. They are usually water or oil-based. This means they’re on the ‘light’ side of the spectrum, and should go into your routine after cleansing, but before moisturizing.
This helps the concentrated ingredients penetrate the skin effectively, as creams and moisturizers are heavier, meaning they can potentially interfere with the serum’s absorption. Depending on your skin type, you may find you get enough moisture from the ampoule step alone if the formula is designed to be hydrating. If your skin is dry or dehydrated, however, you may want to use a moisturizer as the final step to help seal in the goodness!
How do I open an ampoule?
Most skin ampoules will come with instructions on the box or packaging, so look carefully before you open them. ISDINCEUTICS ampoules use the following set of instructions, which you can use to safely open an ampoule during your daily skincare routine.
1. Shake the ampoule
Gently shake the ampoule to ensure the contents mix well. This is especially important for serums which are oil-based. Lightly flick or tap the neck of the ampoule to ensure the serum inside settles to the bottom of the vial.

2. Break open the ampoule
In order to safely open the ampoule, insert it into the protective tube. To break the seal, push down, using the protective tube, making sure to push down from the side furthest away from you.

3. Prepare the vial
Place the special applicator tip onto the now opened ampoule. Do not dispense the serum without using the applicator tip, as the vial is made from delicate glass. Once the applicator tip is securely in place, you can remove the cap and dispense the serum inside.

4. Apply the serum
Gently massage ½ of the contents of the ampoule into the skin.

How do I apply an ampoule?
Once you have correctly opened the ampoule and prepared it, it’s time to apply the serum within! Dispense ½ of the serum into the palm of your hand, and slowly begin to massage it into your skin, over the face, neck, and neckline, avoiding the eye area. Massage the serum in slowly, enjoying the moment of self care, and moving in gentle circles until complete absorption.
Place the cap back onto the applicator tip, to be stored on your vanity, or on a bathroom shelf until the next application. ISDINCEUTICS ampoules should be used within 48h after opening, so you can use the same ampoule in your skincare routine the following morning or evening, depending on the type of ampoule you’re using.
Now you’ve seen how easy it is to add ampoules to your skincare routine, it’s time to find the best one for your skin type! Discover which ISDINCEUTICS ampoule will best fit in to your daily routine here.