When we think about skin that feels hydrated, balanced, and healthy, one ingredient often comes to mind: niacinamide. You’ve likely already spotted it on a few of your favorite products’ labels. But just what makes it so popular, and how does it work?
The answer is in its versatility. Niacinamide offers multiple benefits, addressing a variety of (common) concerns at once. Uneven tone or dark spots? It can help. Sensitive skin? It soothes and comforts. Looking to smooth the appearance of fine lines? It’s ready to step up.
That’s why niacinamide has become a must-have for any routine aimed at achieving healthy, luminous skin. Today we’ll share everything you need to know: what it is, how to combine it with other ingredients, which format is best for your skin type, and more.
NIACINAMIDE (NAM)
| WHAT IT IS: | A form of vitamin B3. |
| WHAT IT DOES: | Helps improve hydration, reduce the look of dark spots and redness, balance excess oil, and smooth wrinkles. |
| WHO IT’S FOR: | Suitable for all skin types. |
| HOW TO USE IT: | Commonly found in both day and nighttime eye creams, serums, and moisturizers. |
| GOES WELL WITH: | Retinal, peptides, carnosine, hyaluronic acid, and gentle exfoliating acids. |
| DON’T MIX WITH: | Vitamin C (ascorbic acid) at the same time. They work best at different pH levels, so use them at different times of day for best results. |
| TRY IT IN: | Melaclear Advanced, Retinal Advanced, Hyaluronic Moisture Sensitive |
Table of Contents
What is niacinamide?
Niacinamide, also known as vitamin B3, is a water-soluble vitamin naturally found in foods such as grains, milk, and meat. In skincare, it stands out amongst the rest for its tolerance and wide range of benefits.
Once absorbed into the skin, niacinamide helps strengthen the barrier function. Studies show that it also works as an antioxidant, helping neutralize free radicals and supporting the skin against daily stressors.
Because our body doesn’t produce enough niacinamide on its own, we get most of it through diet and skincare.
Why is it (seemingly) everywhere in skincare?
The short answer? It’s a true multitasker, combining multiple benefits, gentle action, and flexibility in formulations:
- Backed by research: Science shows that niacinamide helps soothe skin, strengthen the barrier, balance excess oil, and minimize the look of pores.
- All-in-one action: From sun-induced spots to blemishes, redness, or dryness—niacinamide adapts to skin concerns across the board.
- Gentle on skin: Unlike stronger ingredients, niacinamide is gentle enough even for sensitive or redness-prone skin.
- Versatility in routines: You’ll find it in cleansers, serums, moisturizers, and sunscreens.
Who should use niacinamide?
Niacinamide is a great choice for every skin type—its benefits can be tailored to specific needs. In normal skin, it helps keep things balanced, hydrated, and radiant while defending against early signs of aging.
For sensitive skin, its soothing qualities make it ideal for skin prone to irritation and redness, offering comfort without compromising tolerance. On the other hand, niacinamide can also help balance excess oil, reduce shine, and minimize the look of enlarged pores—all while hydrating drier areas at the same time (a strong point for oily and combination skin).
Another thing to consider? Discoloration can show up no matter your skin tone or type. Niacinamide works on multiple fronts to soften dark spots or patches, leading to a more even complexion over time.
When and how to use niacinamide
Niacinamide can be added into both your morning and nighttime routine. Depending on your skin’s needs, you may opt for different product formats:
- Eye creams: To comfort the delicate under-eye area.
- Serums: Highly concentrated formulas that deliver visible results.
- Moisturizers: Ideal for hydration and barrier support.
- Sunscreens: For added skin support and tone-unifying benefits.
Can you combine it with other ingredients?
Definitely. In fact, that’s one of its strengths. Niacinamide pairs well with a few of your current (or soon-to-be) favorites:
- Niacinamide + hyaluronic acid: A hydrating power couple. While hyaluronic acid retains water in the skin, niacinamide helps support barrier function for long-lasting comfort.
- Niacinamide + retinal: Ideal for well-aging routines. Retinal (a form of vitamin A) supports skin renewal, while niacinamide helps minimize visible redness and dryness.
- Niacinamide + zinc PCA: Great for oily or blemish-prone skin, this duo helps balance and calm the skin.
- Niacinamide + tranexamic acid: A brightening combination to help improve the appearance of uneven skin tone and dark spots.
Expert tip: To get the most from niacinamide, use it separately from vitamin C. Try vitamin C in the morning and niacinamide in the evening. These two prefer different pH levels, so combining them at once can offset the benefits.
Find your perfect niacinamide product
No matter your skin type or goal, this standout ingredient deserves a place in your skincare routine. Find an ISDIN formula (or two) that’s right for you:
| Product | Best for | Benefits | Key ingredients | When to use |
|---|---|---|---|---|
| Melaclear Advanced | Dark spots, uneven tone | Helps reduce and limit the appearance of dark spots, while brightening | Niacinamide, tranexamic acid, 4-N-butylresorcinol, exfoliating acids | Morning and evening, 3 months for best results |
| Retinal Advanced | Visible signs of skin aging, wrinkles | Smooths wrinkles and supports radiance | Niacinamide, retinal, bakuchiol, melatonin | Nighttime, with gradual introduction |
| Hyaluronic Moisture Sensitive | Sensitive skin | Hydrates deeply and helps calm redness | Niacinamide, hyaluronic acid, vitamin E | Morning and evening, after your serum |
A few more FAQs
Can I use niacinamide every day?
Yes, niacinamide is gentle enough for daily use, both morning and evening. But it’s always best to follow your product label’s instructions.
How long until I see results?
Consistency is key. Improvements in tone, texture, and hydration are often noticeable after a few weeks of use. Remember, your skin naturally renews itself about every 28 days—so typically, you’ll start to notice results around then. It also depends on the product you choose and whether your daily habits boost or hinder your routine.
Can I use niacinamide with retinol or retinal?
Yes. Niacinamide complements retinoids, helping to minimize potential dryness or redness. Together, they work to gently rejuvenate the skin.
Your skin at its best
Your skin is unique and beautiful just as it is. Skincare ingredients aren’t here to change it—but to care for it, protect it, and bring out its natural glow. Think of niacinamide as a gentle partner, helping you keep your skin healthy and radiant (its natural state).
And don’t forget: beautiful skin also starts from within. Aim to eat well, sleep well, and stay hydrated. Combine these daily habits with your favorite products, and your skin will look and, more importantly, feel its best.
Behind the blog:
Article written and reviewed by:
Our namesake embodies the spirit of embracing life and all its wonder. As wellness journalists, we explore topics that invigorate the senses and keep curiosity alive. We believe that glowing skin is the result of a healthy body and mind. Weaving beauty with science, we aim to inspire you to live young at every age.
