{"id":4920,"date":"2024-07-03T13:50:48","date_gmt":"2024-07-03T13:50:48","guid":{"rendered":"https:\/\/www.isdin.com\/en-US\/blog\/?p=4920"},"modified":"2025-09-18T10:22:59","modified_gmt":"2025-09-18T10:22:59","slug":"whats-glycation-and-how-to-fight-it","status":"publish","type":"post","link":"https:\/\/www.isdin.com\/us\/blog\/skincare\/moisturizers\/whats-glycation-and-how-to-fight-it\/","title":{"rendered":"What&#8217;s Glycation and How Can You Fight It?"},"content":{"rendered":"<span class=\"span-reading-time rt-reading-time\" style=\"display: block;\"><span class=\"rt-label rt-prefix\">Reading:<\/span> <span class=\"rt-time\"> 3<\/span> <span class=\"rt-label rt-postfix\">minutes<\/span><\/span>\n<p><\/p>\n\n\n\n<p>Doctors, dentists, nutritionists \u2014 most experts agree that limiting sweets can help keep you feeling healthy and vibrant overall. But, what about sugar and your skin? Can that perfect piece of chocolate cake lead to signs of skin aging down the line?<\/p>\n\n\n\n<p>As it turns out, sugar is a key player in the skin\u2019s aging process. And that\u2019s where <em><strong>glycation<\/strong><\/em>&nbsp;comes in. With the help of experts, we\u2019re here to explain the definition of glycation and uncover just how much (or little) sugar can contribute to skin aging.<\/p>\n\n\n\n<p>Let\u2019s get started.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-what-is-glycation\">What is glycation?<\/h2>\n\n\n\n<p>Glycation is a natural process in your body that\u2019s triggered by sugars, like glucose or fructose. When there\u2019s too much sugar inside the skin fibers, the sugar molecules adhere to skin\u2019s\u00a0<a href=\"https:\/\/www.isdin.com\/us\/blog\/skincare\/layers-and-functions-of-skin\/\">collagen and elastin proteins<\/a>. And these hero proteins are responsible for keeping skin firm and supple.<\/p>\n\n\n\n<p>What happens next? When these important proteins get weighed down by sugar, your body responds with other processes that can result in inflammation and signs of skin aging. (1)<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-how-does-glycation-cause-skin-aging\">How does glycation cause skin aging?<\/h3>\n\n\n\n<p>The glycation process causes something called <strong>advanced glycation end-products (AGEs)<\/strong> to form in your skin. In turn, these AGEs can play a major role in skin aging. (2) The end-products make <a href=\"https:\/\/www.isdin.com\/us\/blog\/skincare\/what-is-collagen-for-skin\/\">collagen<\/a> rigid over time, meaning that it loses its ability to keep skin bouncy. As a result, you might notice fine lines and wrinkles as skin loses its natural structural support. (1)<\/p>\n\n\n\n<p>Another effect of glycation? Inflammation. As the process continues, AGEs start to interact with other receptors in your skin. These interactions can kick up inflammation, resulting in dryness or discomfort. (1)<a href=\"\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"618\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"https:\/\/www.isdin.com\/en-US\/blog\/wp-content\/uploads\/2023\/05\/2024_06_Glycation_IMG01.jpg\" alt=\"Does sugar cause skin aging?\" class=\"wp-image-9951 lazyload\"\/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-when-does-glycation-occur-and-why\">When does glycation occur and why?<\/h3>\n\n\n\n<p>Glycation is a natural process. Typically, it begins at around age 20 and gradually intensifies. But some factors can accelerate glycation like:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Certain medical conditions, such as diabetes<\/li>\n\n\n\n<li>Exposure to <a href=\"https:\/\/www.isdin.com\/us\/blog\/skincare\/ultraviolet-radiation-and-your-skin\/\"><strong>UV radiation<\/strong><\/a> from the sun<\/li>\n\n\n\n<li>Smoking, pollution, and other <strong><a href=\"https:\/\/www.isdin.com\/us\/blog\/skincare\/what-is-the-exposome-and-why-it-is-important-to-protect-yourself-from-the-sun\/\">external skin stressors<\/a><\/strong><\/li>\n\n\n\n<li>Diets&nbsp;<strong>high in sugar<\/strong><\/li>\n\n\n\n<li>Diets <strong>high in fried foods:<\/strong> AGEs can form in foods that have been exposed to high temperatures during grilling, frying, or toasting.<\/li>\n<\/ul>\n\n\n\n<p>These factors can cause more AGEs to form in the skin, resulting in a loss of firmness and elasticity. (1)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-how-can-you-help-fight-glycation\">How can you help fight glycation?<\/h2>\n\n\n\n<p>Here\u2019s the good news. There are steps you can take to help combat glycation and its aging effects on your skin. Let\u2019s dive in.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><a href=\"https:\/\/www.isdin.com\/us\/p\/age-contour\/3116\"><img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"618\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"https:\/\/www.isdin.com\/en-US\/blog\/wp-content\/uploads\/2023\/05\/2024_06_Glycation_IMG03.jpg\" alt=\"ISDIN Age Contour Anti-Glycation Cream\" class=\"wp-image-9950 lazyload\"\/><\/a><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-use-targeted-skincare-formulas\">Use targeted skincare formulas<\/h3>\n\n\n\n<p>Get proactive with your daily skincare routine. Opt for <strong>products including carnosine, a powerful anti-glycation agent.<\/strong><\/p>\n\n\n\n<p>How does carnosine work to fight against the formation of AGEs? Through distraction. The glucose molecules stick to the carnosine instead of your collagen, slowing down the glycation process. Carnosine also acts as an antioxidant, helping to combat the <a href=\"https:\/\/www.isdin.com\/en-US\/blog\/skincare\/what-are-free-radicals-how-do-they-affect-skin\/\">effects of free radicals on your skin<\/a> and minimize the visible signs of aging. (1)<\/p>\n\n\n\n<p>Isdinceutics Age Contour was designed as a triple threat: providing antioxidant support, helping to minimize the look of&nbsp;<a href=\"https:\/\/www.isdin.com\/en-US\/blog\/skincare\/how-to-get-rid-of-forehead-wrinkles\/\">fine lines and wrinkles<\/a>, and with carnosine as a key ingredient, fighting the formation of AGEs in the skin. Apply the rich moisturizing formulas in both the <a href=\"https:\/\/www.isdin.com\/en-US\/face-care\/face-neck-firming-cream-isdinceutics-age-contour-8429420134928.html\">morning<\/a> and <a href=\"https:\/\/www.isdin.com\/en-US\/face-care\/night-cream-isdinceutics-age-contour-8429420199064.html\">evening<\/a> for visible results.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-refine-your-diet\">Refine your diet<\/h3>\n\n\n\n<div class=\"wp-block-media-text alignwide has-media-on-the-right is-stacked-on-mobile\"><div class=\"wp-block-media-text__content\">\n<p><\/p>\n\n\n\n<p>Are you getting enough fruits and vegetables? Studies show that glycation (and the effects on your skin that come along with it) may be reduced by managing blood sugar levels. And the best place to start is with a healthy, balanced diet. (1)<\/p>\n\n\n\n<p>If you\u2019re concerned about how much sugar you\u2019re consuming, it\u2019s always best to consult a professional. They can advise you on dietary changes and recommend ways to cut down on your sugar intake if needed.<\/p>\n<\/div><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"670\" height=\"754\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"https:\/\/www.isdin.com\/en-US\/blog\/wp-content\/uploads\/2023\/05\/Sugar-and-your-skin-glycation-ISDIN.png\" alt=\"Sugar and your skin glycation ISDIN\" class=\"wp-image-8711 size-full lazyload\" data-sizes=\"auto\" data-srcset=\"https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Sugar-and-your-skin-glycation-ISDIN.png 670w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Sugar-and-your-skin-glycation-ISDIN-267x300.png 267w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Sugar-and-your-skin-glycation-ISDIN-133x150.png 133w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Sugar-and-your-skin-glycation-ISDIN-450x506.png 450w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Sugar-and-your-skin-glycation-ISDIN-225x253.png 225w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Sugar-and-your-skin-glycation-ISDIN-20x23.png 20w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Sugar-and-your-skin-glycation-ISDIN-85x96.png 85w\" sizes=\"auto, (max-width: 670px) 100vw, 670px\" \/><\/figure><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-turn-to-proper-sun-protection\">Turn to proper sun protection<\/h3>\n\n\n\n<p>Sun spots, wrinkles, skin sagging: many signs of aging can be attributed to sun exposure, AKA <a href=\"https:\/\/www.isdin.com\/en-US\/blog\/skincare\/anti-aging\/what-is-photoaging-and-why-do-we-have-to-care-about-it\/\">photoaging<\/a>. And glycation is no exception. <a href=\"https:\/\/www.tandfonline.com\/doi\/full\/10.4161\/derm.22028\">Scientists have found<\/a> that AGEs build up in sun-exposed skin, contributing to the visible signs of aging.<\/p>\n\n\n\n<p>Our favorite reminder to help protect your skin? Remember to wear broad spectrum sunscreen every day. <a href=\"https:\/\/www.isdin.com\/en-US\/blog\/skincare\/sunscreen-faqs-your-questions-answered\/\">Proper sun protection<\/a> can help slow the signs of skin aging, and more importantly, help protect against skin cancer.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"527\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"https:\/\/www.isdin.com\/en-US\/blog\/wp-content\/uploads\/2023\/05\/Protect-your-skin-with-ISDIN-sunscreen-1024x527.png\" alt=\"Protect your skin with ISDIN sunscreen\" class=\"wp-image-8712 lazyload\" data-sizes=\"auto\" data-srcset=\"https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Protect-your-skin-with-ISDIN-sunscreen-1024x527.png 1024w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Protect-your-skin-with-ISDIN-sunscreen-300x155.png 300w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Protect-your-skin-with-ISDIN-sunscreen-150x77.png 150w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Protect-your-skin-with-ISDIN-sunscreen-768x396.png 768w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Protect-your-skin-with-ISDIN-sunscreen-585x300.png 585w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Protect-your-skin-with-ISDIN-sunscreen-450x232.png 450w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Protect-your-skin-with-ISDIN-sunscreen-20x11.png 20w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Protect-your-skin-with-ISDIN-sunscreen-225x116.png 225w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Protect-your-skin-with-ISDIN-sunscreen-900x464.png 900w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Protect-your-skin-with-ISDIN-sunscreen-186x96.png 186w, https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/Protect-your-skin-with-ISDIN-sunscreen.png 1200w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>And above all, love your skin, care for it, and protect it, always.<\/strong><\/p>\n\n\n\n<p style=\"font-size:10px\"><strong>Sources:<\/strong><br>1  Ichihashi, M., Yagi, M., Nomoto, K., &amp; Yonei, Y. (2011). Glycation Stress and Photo-Aging in Skin. <em>Anti-aging Medicine<\/em>, <em>8<\/em>(3), 23\u201329. https:\/\/doi.org\/10.3793\/jaam.8.23<br><br>2 Gkogkolou, P., B\u00f6hm, M. Advanced glycation end products: Key players in skin aging? In <em>Dermatoendocrinology&nbsp;<\/em>(2012); 4(3): 259-270.<br><br>3 Ghodsi, R., &amp; Kheirouri, S. (2018). Carnosine and advanced glycation end products: a systematic review. <em>Amino Acids<\/em>, <em>50<\/em>(9), 1177\u20131186. https:\/\/doi.org\/10.1007\/s00726-018-2592-9<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>As it turns out, sugar is a key player in the skin\u2019s aging process. We\u2019re here to explain the definition of glycation and how sugar can contribute to skin aging.<\/p>\n","protected":false},"author":68,"featured_media":9952,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"image","meta":{"_uag_custom_page_level_css":"","footnotes":""},"categories":[2460,355,2461],"tags":[2425,2424,2422,2423,2421],"class_list":["post-4920","post","type-post","status-publish","format-image","has-post-thumbnail","hentry","category-anti-aging","category-moisturizers","category-skincare","tag-carnosine","tag-elastin","tag-glycation","tag-sugar-and-skin","tag-your-skin","post_format-post-format-image"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.4 (Yoast SEO v25.5) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>What&#039;s Glycation and How Can You Fight It? | ISDIN<\/title>\n<meta name=\"description\" content=\"With the help of experts, we\u2019re here to explain the definition of glycation and how sugar can contribute to skin aging.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.isdin.com\/us\/blog\/skincare\/moisturizers\/whats-glycation-and-how-to-fight-it\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What&#039;s Glycation and How Can You Fight It?\" \/>\n<meta property=\"og:description\" content=\"With the help of experts, we\u2019re here to explain the definition of glycation and how sugar can contribute to skin aging.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.isdin.com\/us\/blog\/skincare\/moisturizers\/whats-glycation-and-how-to-fight-it\/\" \/>\n<meta property=\"og:site_name\" content=\"ISDIN Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/isdinusa\/\" \/>\n<meta property=\"article:published_time\" content=\"2024-07-03T13:50:48+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-09-18T10:22:59+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/2024_06_Glycation_IMG02.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"760\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Live Young\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@isdinusa\" \/>\n<meta name=\"twitter:site\" content=\"@isdinusa\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Live Young\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.isdin.com\/us\/blog\/skincare\/moisturizers\/whats-glycation-and-how-to-fight-it\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.isdin.com\/us\/blog\/skincare\/moisturizers\/whats-glycation-and-how-to-fight-it\/\"},\"author\":{\"name\":\"Live Young\",\"@id\":\"https:\/\/www.isdin.com\/us\/blog\/#\/schema\/person\/946bb6e0fd3b11c522851e10958cb42c\"},\"headline\":\"What&#8217;s Glycation and How Can You Fight It?\",\"datePublished\":\"2024-07-03T13:50:48+00:00\",\"dateModified\":\"2025-09-18T10:22:59+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.isdin.com\/us\/blog\/skincare\/moisturizers\/whats-glycation-and-how-to-fight-it\/\"},\"wordCount\":769,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/www.isdin.com\/us\/blog\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.isdin.com\/us\/blog\/skincare\/moisturizers\/whats-glycation-and-how-to-fight-it\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.isdin.com\/us\/blog\/wp-content\/uploads\/2023\/05\/2024_06_Glycation_IMG02.jpg\",\"keywords\":[\"carnosine\",\"elastin\",\"glycation\",\"sugar and skin\",\"your skin\"],\"articleSection\":[\"Anti aging\",\"Moisturizers\",\"Skincare\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.isdin.com\/us\/blog\/skincare\/moisturizers\/whats-glycation-and-how-to-fight-it\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.isdin.com\/us\/blog\/skincare\/moisturizers\/whats-glycation-and-how-to-fight-it\/\",\"url\":\"https:\/\/www.isdin.com\/us\/blog\/skincare\/moisturizers\/whats-glycation-and-how-to-fight-it\/\",\"name\":\"What's Glycation and How Can You Fight It? 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