Melaclear Advanced Eco-Refill

Dark spot corrector with lasting results



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Refill Melaclear Advanced with its Eco-Refill, a specially-designed replacement that allows you to reuse the original packaging. Daily use reduces dark spots with notable results as early as two weeks and remarkable results within 12 weeks. Achieve lasting radiance with its blend of complexion-unifying ingredients, including tranexamic acid, niacinamide, and Spot Corrector Complex.

1.7 FL OZ (50mL)

All skin types

Dermatologist tested. Silky gel-serum texture.

Dark spots, uneven pigmentation, stubborn discoloration

Spot Corrector Complex, tranexamic acid, niacinamide, licorice root extract

Fade discoloration, recapture radiance
Whatever your skin type, target stubborn discoloration with this expert serum designed to reduce unwanted dark spots.
Reduces the amount and size of existing dark spots to unify overall skin tone.
Promotes skin renewal, increasing luminosity and balancing tone with long-lasting results.
Boosts hydration and reinforces the skin’s barrier function.
Visible results after just 1 bottle¹


After 12 weeks, clinical results showed¹:
Decrease in facial hyperpigmentation
Improvement in luminosity
After twice-daily use, consumers said²:
Saw a brighter complexion
Saw fewer dark spots
¹Clinical Study to evaluate the efficacy of Melaclear Advanced after 12 weeks of twice-daily use.
²Consumer testing reported after 4 weeks of twice-daily use. Data on file. ISDIN Corp. 2023. Morristown, NJ.


A powerful blend of pigment-perfecting ingredients
Tranexamic acid
A synthetic amino acid derived from lysine that helps fight dark spots, especially those caused by the sun.
This hero ingredient targets unwanted pigmentation and improves skin hydration.
Spot Corrector Complex
Our expert blend of exfoliating acids renews skin, while a highly effective tyrosinase-inhibitor treats discoloration.
Licorice root extract
A naturally-derived ingredient that soothes skin and helps to preserve hyaluronic acid levels, boosting flexibility.

How to use

The star of your brightening skincare routine
Once you’ve used up all of your Melaclear Advanced, easily replace the original unit with the Eco-Refill. Apply morning and night onto clean, dry skin. Gently spread 1-2 pumps of serum onto your face, neck, and dècolletage, avoiding the eye area. Always use in combination with daily broad spectrum sunscreen, such as Eryfotona Actinica or Eryfotona Ageless.
1. Cleanse
Apply morning and night onto clean, dry skin.
2. Massage
Spread 1-2 pumps of serum onto your face and neck, avoiding the eye area.
3. Protect
Always use in combination with broad spectrum sunscreen.
Add Melaclear Advanced to your routine
Include Melaclear Advanced in your daily skincare routine for luminous, even skin.
Wash your face with your go-to cleanser.
Eye cream
Massage your eye cream into the eye contour.
Boost your routine with Melaclear Advanced.
Face cream
Apply a hydrating face cream to lock in moisture.
Sun protection
Protect your skin with your daily sunscreen.


Refill your serum as many times as you’d like
Melaclear Advanced’s innovative Eco-Refill packaging helps reduce the environmental impact associated with the use of this product.
Emits 78% less CO2.¹
Reduces water use by 80%.¹
Reduces weight of packaging by 88%.²
Consumes 74% less energy.¹
¹Percentage difference in CO2 emissions, water use, and energy use between the full retail product and the refill in relation to the life cycle of the packaging. ²Percentage difference in the weight of the packaging (glass, plastic, cardboard) between the full retail product and the refill.